Mastic gum benefits: what the research shows

Mastic gum is best researched for oral health and digestion, with promising but lighter evidence for H. pylori, cholesterol, and blood sugar, and early lab-only research on several more potential health benefits.
- Oral and dental health: strong human research
- Digestion: strong human research
- Reflux: limited human evidence
- H. pylori: limited human evidence
- Jaw and facial muscles: limited human evidence
- Heart and metabolic markers: limited human evidence
- Effects on cancer, sperm and testosterone, asthma, and atherosclerosis: early lab research
What is mastic gum good for?
Oral and dental health
Oral health is the strongest-evidenced benefit of mastic gum.
Two clinical studies showed that chewing mastic gum reduced oral bacteria, plaque levels, and gum-inflammation scores.12
Lowering harmful bacteria and getting rid of plaque prompts overall healthier oral conditions like better breath.
Digestion, reflux, and H. pylori

The Dabos 2010 trial tested the efficacy of mastic gum in 148 patients with functional dyspepsia. Mastic gum improved several symptoms including heartburn.3
In a randomized pilot study the same year, 52 H. pylori patients took mastic gum for symptom relief and support. Pure mastic eradicated the infection in roughly a third of the patients.4
When added to standard H. pylori triple therapy in another study, mastic gum capsules cleared the infection in 83 of 90 patients.5
Mastic gum has many other gut benefits, which you can read about in our detailed explanation.
Jaw and facial muscles
Any mastic gum chewer can attest to the fact that it is hard and chewy, making it an effective resistance training for the jaw muscles.
It primarily works the masseter muscles. Chewing mastic gum can make your jaw muscles stronger, healthier, and, in some cases, bigger. Larger masseters widen the jaw, resulting in a sharper, more defined jawline when body fat is low enough for the muscle to show. By contrast, regular chewing gum is too soft and lacks the necessary resistance to work the masseters.
Heart and metabolic markers
A prospective, randomized pilot study by Kartalis in 2016 found that 1 gram of mastic gum capsules a day modestly lowered total cholesterol levels and fasting plasma glucose levels.6
It was most effective for overweight and obese patients.
Early mastic research: experimental and unproven benefits
Mastic gum has some potential benefits that are based on lab-only or animal-only research. The research on mastic affecting cancer, sperm and testosterone, asthma, and atherosclerosis is tentative.
- Researchers are looking at mastic compounds and cancer cells together. No human research has been conducted.
- A human trial on male sexuality and prostate function singled out zinc as a mastic gum compound that can potentially boost testosterone levels.7
- The only evidence we have that mastic may help asthma comes from a trial performed on asthmatic model mice.8
- The Kartalis research on cholesterol indicates a possibility that mastic gum can help atherosclerosis, but no research has studied it specifically.6
Is it safe and who should be careful?

For most people, mastic gum is generally considered safe.
Few studies have reported adverse side effects, and those that did reported only minor or short-term ones. There have not been any documented allergies from oral consumption of mastic resin. Though mastic resin and pistachios come from the same Pistacia genus, there is nothing in mastic resin that poses a problem for those with nut allergies.
The biggest problem customers encounter with mastic gum is jaw soreness, not any health complaint. Even then, the soreness is usually mentioned positively as it indicates a good jaw workout.
Digestive complaints are rare and generally mild when they do come up. That being said, you may want to exercise caution if you have TMJ; a pre-existing mouth, jaw, teeth, or stomach condition; or a sensitive stomach that’s easily upset.
When to chew vs. take capsules and what to realistically expect
Use mastic chewing gum for:
- Oral and dental health
- Jaw and facial muscle development
- Reflux improvement
Mastic gum capsules are more effective for:
- Digestive health
- H. pylori treatment
- Lowering cholesterol and glucose levels
Don’t expect to see results instantly. It can take a few weeks on average to see any benefits from mastic gum, and the best results come from months to years of consistent chewing.
We recommend starting with our Chios mastic gum, as you can reap the most benefits from chewing.

FAQs about mastic gum benefits
What is mastic gum good for?
Mastic gum has many benefits, mainly for oral health. Other notable benefits include improving digestive health, improving reflux and H. pylori, lowering cholesterol and strengthening jaw and facial muscles. Studies have tentatively named benefits for cancer, sperm and testosterone, and asthma, but the only research we have on those is early and still experimental.
What are the downsides of mastic gum?
Certain people may experience unwanted jaw soreness, mild digestive issues, or dental work loosening from chewing. Not everyone experiences these. Some customers also complain about not liking the texture and taste of mastic gum.
Can you take mastic gum every day?
Yes, it is safe to take every day, but you should work your way up to that. It’s important to start small. To learn more about recommended chewing guidelines, visit our page on how long to chew.
How long does it take for mastic gum to work?
This can vary from person to person. Most people see small results after two-three weeks. It can take months for the full effects to become noticeable.
Does mastic gum get rid of Candida?
Various studies tested the efficacy of mastic gum in killing Candida, but they all tested in petri dishes, not on people. They saw varying levels of success in killing and stopping the spread of Candida. So the resin has been found effective against Candida, but they have yet to test on humans.
Is Chios mastic gum better than regular mastic gum?
Real mastic gum comes exclusively from the Greek island of Chios. If you find “mastic” gum that’s not made of pure resin from Chios, it’s not real mastic. Certain brands, such as Falim Gum, sell “mastic gum” that is just flavored with a piney mastic taste.
This article originally appeared online in 2024; it was most recently updated on June 29, 2026, to include current information.

Beatrix Turajski
Beatrix is a health and wellness writer with two blogs and a special passion for mental health, fitness, and nutrition. Her career has taken her from creative writing to interning to freelancing.
References
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Takahashi, K., et al. “A pilot study on antiplaque effects of mastic chewing gum in the oral cavity.” Journal of Periodontology Volume 74, 4(2003): 501-505. doi.org ↩
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Aksoy, A., et al. “Short-term effect of mastic gum on salivary concentrations of cariogenic bacteria in orthodontic patients.” The Angle Orthodontist Volume 77, 1(2007): 124-128. doi.org ↩
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Dabos, K.J., et al. “Is Chios mastic gum effective in the treatment of functional dyspepsia? A prospective randomised double-blind placebo controlled trial.” Journal of Ethnopharmacology 127, 2(2010): 205-209. doi.org. ↩
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Dabos, K. J., et al. “The Effect of Mastic Gum on Helicobacter pylori: A Randomized Pilot Study.” Phytomedicine Volume 17, 3-4(2010): 296-299. doi.org. ↩
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Addissouky, T. A., et al. “Assessing the Efficacy of a Modified Triple Drug Regimen Supplemented with Mastic Gum in the Eradication of Helicobacter pylori Infection.” American Journal of Clinical Pathology Volume 160, Suppl. 1(2023): S19. doi.org. ↩
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Kartalis, A., et al. “Effects of Chios mastic gum on cholesterol and glucose levels of healthy volunteers: A prospective, randomized, placebo-controlled, pilot study (CHIOS-MASTIHA)” European Journal of Preventive Cardiology Volume 23, 7(2016): 722-729. doi.org ↩ ↩2
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Sawidis, T., Yurukova L., Askitis T. “Chios mastic, a natural supplement for zinc to enhance male sexuality and prostate function.” Pharmaceutical Biology Volume 48, 1(2010): 48-54. doi.org ↩
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Qiao, J., et al. “Mastic Alleviates Allergic Inflammation in Asthmatic Model Mice by Inhibiting Recruitment of Eosinophils.” American Journal of Respiratory Cell and Molecular Biology Volume 45, 1(2011): 95-100. doi.org ↩